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CRISPR-Based Gene Editing Technique Can Insert Entire Genes Into Cells
Research News

CRISPR-Based Gene Editing Technique Can Insert Entire Genes Into Cells

Researchers at the Broad Institute of MIT and Harvard have developed a new version of prime editing that can install or swap out gene-sized DNA sequences. First developed in 2019, prime editing is a precise method of making a wide diversity of gene edits in human cells, including small substitutions, insertions, and deletions.

AI Tool Eve Accurately Predicts Disease Relevance of Human Genetic Variants
Research News

AI Tool Eve Accurately Predicts Disease Relevance of Human Genetic Variants

Researchers at Harvard Medical School and Oxford University have now developed an artificial intelligence (AI) tool called EVE (evolutionary model of variant effect), which uses a sophisticated type of machine learning to detect patterns of genetic variation across hundreds of thousands of nonhuman species and then use them to make predictions about the meaning of variations in human genes.

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